The American Association for the Study of Liver Diseases (AASLD) Foundation funds research to advance the science and practice of hepatology, and to improve liver health and quality patient care. Learn more about some of the research we support by exploring the researchers and projects below.

ALCOHOL-ASSOCIATED LIVER DISEASE

Role Of BTK Signalosome in Alcoholic Liver Disease 
Prashanth Thevkar Nagesh, 2021 Afdhal/McHutchison LIFER Award
Status: Completed

Defining Phenotypes of Alcohol-Related Liver Disease
Allison Kwong, 2020 Clinical, Translational, and Outcomes Research Award in Liver Diseases
Status: Completed

Intestinal Stem-Cell Proliferation and Differentiation in Alcoholic Liver Disease
Ana Cristina Llorente-Izquierdo, 2018 Pinnacle Research Award in Liver Diseases
Status: Completed

AUTOIMMUNE LIVER DISEASES (PBC, PSC, AUTOIMMUNE HEPATITIS) 

The Therapeutic Role of Neurokinin-1 Receptor Antagonist in Primary Sclerosing Cholangitis
Konstantina Kyritsi, 2022 Gupta Family Pilot Award in PSC Research
Status: Completed

The Gut Microbiome in Autoimmune Liver Diseases Liver Transplant Rejection
Yael R. Nobel, 2022 Autoimmune Liver Diseases Exploratory Research Award 
Status: Completed

Contribution of Microbiome in Environmental Agent Trichloroethylene-Mediated Autoimmune Hepatitis
Hui Wang, 2021 Autoimmune Liver Diseases Exploratory Research Award 
Status: Completed

Role of Microbiome in Development of Offspring Cholestatic Liver Disease after Maternal Obesogenic Diet Exposure
Michael Thompson, 2021 Gupta Family Pilot Award in PSC Research
Status: Completed

Repertoire Analysis of Human AMA in Primary Biliary Cholangitis
Weici Zhang, 2017 Pinnacle Research Award in Liver Diseases
Status: Completed

METABOLIC Liver Disease

Nonviral Delivery of Crispr-Cas9 into Hepatocytes for Liver Repopulation Using Acetaminophen Selection
Renee Cottle, 2021 Pinnacle Research Award
Status: Active

Fibrogenesis and Non-Parenchymal Cell Biology

Hippo-YAP Pathway, Ferroptosis of Hepatic Stellate Cells and Liver Fibrosis
Kuo Du, 2021 Pinnacle Research Award
Status: Active

Health Services and Public Health Research

LiverPal: A Randomized Study of Inpatient Palliative Care for Patients with End-Stage Liver Disease
Nneka Ufere, 2021 Clinical, Translational, and Outcomes Research Award
Status: Completed

Hepatobiliary Neoplasia / Hepatocellular Carcinoma (HCC/Liver cancer)

Incorporating the Patient Voice into Hepatocellular Carcinoma Treatment Models
Andrew Moon, 2022 Clinical, Translational, & Outcomes Research Award in Liver Diseases
Status: Completed

Combating Socioeconomic Disparities in Hepatocellular Carcinoma Through Geographic Late Stage Hotspots
Kali Zhou, 2021 Clinical, Translational, & Outcomes Research Award in Liver Diseases
Status: Completed

Functions and Mechanisms of METTL16 in HCC pathogenesis
Rui Su, 2022 Pinnacle Research Award in Liver Diseases
Status: Active

Development and validation of models that estimate risk of hepatocellular carcinoma in patients with nonalcoholic fatty liver disease and cured hepatitis C virus infection
Philip Vutien, 2022 Clinical, Translational, & Outcomes Research Award in Liver Diseases
Status: Active

Mechanistic Analysis of Zfp791 Functions in Hepatocellular Carcinoma
Jin Lee, 2021 Pinnacle Research Award in Liver Diseases
Status: Active

Hepatorenal Syndrome & Hepatoadrenal syndrome 

Application of Novel Biomarkers of Chronic Kidney Disease to Stratify Risk for Type 1 Hepatorenal Syndrome
Giuseppe Cullaro, 2021 Clinical, Translational, and Outcomes Research Award in Liver Diseases
Status: Completed

Defining the Mechanisms Behind and Prognosis of Adrenal Insufficiency in Cirrhosis
Brian Wentworth, 2021 Clinical, Translational, and Outcomes Research Award in Liver Diseases
Status: Completed